Overview

The AVANZA team has experience dating back to the early 1990's performing a wide variety of in vivo toxicology studies that examine the safety of vaccines. These studies are performed in our AAALAC accredited Biosafety Level-2 (BSL-2) laboratory with an experienced in-life and post-life staff.

 

Vaccine Studies

• Biodistribution and integration studies

• General toxicology/safety studies

• Immunogenicity studies

• In vivo adjuvant selection studies

• Potency studies

• Proof-of-concept studies

Vaccine Types

• DNA plasmid

• Live attenuated

• Peptide

• Prime-boost strategies

• Recombinant protein

• Recombinant vector

• Virus-like particle

Routes of Administration Dermal (patch) Intradermal (Biojector, electroporation) Intramuscular (Biojector) Intranasal Intravesicular Subcutaneous Other methods     Click here for a printable summary sheet.

Vaccine Experience Facility with BSL-2 ratings In-life team Necropsy team Over 130 general vaccine toxicity studies, including: Ebola, HIV, dengue, plague, WNV, SARS, malaria, Botulin toxin, several cancers, etc. Over 40 biodistribution studies using sterile necropsy techniques Biodistribution necropsy (sterilized necropsy techniques) Clinical pathology analyses Histopathology evaluation